Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the...
Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Securin overexpression correlates with poor prognosis in various tumours. We have previously shown that securin depletion promotes radiation-induced senescence and enhances radiosensitivity in human cancer cells. However, the underlying molecular mechanisms and the paracrine effects remain unknown. In this study, we showed that radiation induced se...
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Full title
Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3628221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3628221
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E-ISSN
2045-2322
DOI
10.1038/srep01675
