Log in to save to my catalogue

The NK1 receptor antagonist L822429 reduces heroin reinforcement

The NK1 receptor antagonist L822429 reduces heroin reinforcement

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3629386

The NK1 receptor antagonist L822429 reduces heroin reinforcement

About this item

Full title

The NK1 receptor antagonist L822429 reduces heroin reinforcement

Publisher

England: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2013-05, Vol.38 (6), p.976-984

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is unknown whether pharmacological NK1R blockade has the same effect. Here, we examined the effect of L822429, a rat-specific NK1R antagonist, on the reinforcing properties of heroin in rats on short (1 h: ShA) or long (12 h...

Alternative Titles

Full title

The NK1 receptor antagonist L822429 reduces heroin reinforcement

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3629386

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3629386

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/npp.2012.261

How to access this item