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A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3633213

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

About this item

Full title

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2012-08, Vol.337 (6097), p.937-941

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Mucus clearance is the primary defense mechanism that protects airways from inhaled infectious and toxic agents. In the current gel-on-liquid mucus clearance model, a mucus gel is propelled on top of a "watery" periciliary layer surrounding the cilia. However, this model fails to explain the formation of a distinct mucus layer in health or why mucu...

Alternative Titles

Full title

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3633213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3633213

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1223012

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