Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in v...
Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive and associated with poor prognosis. Basic research to develop new treatment regimens is critically needed.
The effects of imatinib mesylate on MPNSTs were examined in six human MPNST cell lines and in a xenograft mouse model.
The results showed expression of platelet-deri...
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Full title
Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3654969
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3654969
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-13-224
