Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of...
Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations
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Oxford: Oxford University Press
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English
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Oxford: Oxford University Press
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Background. Fluconazole (FLC) resistance is common in C. glabrata and echinocandins are often used as first-line therapy. Resistance to echinocandin therapy has been associated with FKS1 and FKS2 gene alterations. Methods. We reviewed records of all patients with C. glabrata bloodstream infection at Duke Hospital over the past decade (2001–2010) an...
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Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3658363
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3658363
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1058-4838,1537-6591
E-ISSN
1537-6591
DOI
10.1093/cid/cit136
