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Glioma‐Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

Glioma‐Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3659661

Glioma‐Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

About this item

Full title

Glioma‐Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

Publisher

United States: AlphaMed Press

Journal title

Stem cells translational medicine, 2012-11, Vol.1 (11), p.811-824

Language

English

Formats

Publication information

Publisher

United States: AlphaMed Press

More information

Scope and Contents

Contents

Control of the cancer stem/initiating cell population is considered key to realizing the long‐term survival of glioblastoma patients. Recently, we demonstrated that FOXO3 activation is sufficient to induce differentiation of glioma‐initiating cells having stem‐like properties and inhibit their tumor‐initiating potential. Here we identified metformi...

Alternative Titles

Full title

Glioma‐Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3659661

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3659661

Other Identifiers

ISSN

2157-6564

E-ISSN

2157-6580

DOI

10.5966/sctm.2012-0058

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