Truncations of Titin Causing Dilated Cardiomyopathy
Truncations of Titin Causing Dilated Cardiomyopathy
About this item
Full title
Author / Creator
Herman, Daniel S , Lam, Lien , Taylor, Matthew R.G , Wang, Libin , Teekakirikul, Polakit , Christodoulou, Danos , Conner, Lauren , DePalma, Steven R , McDonough, Barbara , Sparks, Elizabeth , Teodorescu, Debbie Lin , Cirino, Allison L , Banner, Nicholas R , Pennell, Dudley J , Graw, Sharon , Merlo, Marco , Di Lenarda, Andrea , Sinagra, Gianfranco , Bos, J. Martijn , Ackerman, Michael J , Mitchell, Richard N , Murry, Charles E , Lakdawala, Neal K , Ho, Carolyn Y , Barton, Paul J.R , Cook, Stuart A , Mestroni, Luisa , Seidman, Christine E and Seidman, J.G
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Titin, an important protein in the sarcomere, is the largest human protein. This study identified mutations in the titin gene that result in a truncated protein as important causes of dilated cardiomyopathy.
Gene mutation is an important cause of cardiomyopathy. Mutations in eight sarcomere-protein genes cause hypertrophic cardiomyopathy, detect...
Alternative Titles
Full title
Truncations of Titin Causing Dilated Cardiomyopathy
Authors, Artists and Contributors
Author / Creator
Lam, Lien
Taylor, Matthew R.G
Wang, Libin
Teekakirikul, Polakit
Christodoulou, Danos
Conner, Lauren
DePalma, Steven R
McDonough, Barbara
Sparks, Elizabeth
Teodorescu, Debbie Lin
Cirino, Allison L
Banner, Nicholas R
Pennell, Dudley J
Graw, Sharon
Merlo, Marco
Di Lenarda, Andrea
Sinagra, Gianfranco
Bos, J. Martijn
Ackerman, Michael J
Mitchell, Richard N
Murry, Charles E
Lakdawala, Neal K
Ho, Carolyn Y
Barton, Paul J.R
Cook, Stuart A
Mestroni, Luisa
Seidman, Christine E
Seidman, J.G
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3660031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3660031
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1110186
