miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cone...
miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Xenopus
retinal ganglion cells show a switch in sensitivity to the guidance cue Sema3A during development. In this study, the authors show that the timing of this switch is determined by a mechanism in which miR-124 regulates the expression of Neuropilin-1 through modulation of the transcription-repressing cofactor CoREST.
During axon pathfin...
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Full title
miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3661270
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3661270
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2979
