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Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnove...

Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnove...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696741

Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover

About this item

Full title

Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.E2352-E2361

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cells are mechanosensitive to extracellular matrix (ECM) deformation, which can be caused by muscle contraction or changes in hydrostatic pressure. Focal adhesions (FAs) mediate the linkage between the cell and the ECM and initiate mechanically stimulated signaling events. We developed a stretching apparatus in which cells grown on fibronectin-coat...

Alternative Titles

Full title

Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696741

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696741

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1221637110

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