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miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696812

miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

About this item

Full title

miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10765-10770

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Polycystic kidney disease (PKD), the most common genetic cause of chronic kidney failure, is characterized by the presence of numerous, progressively enlarging fluid-filled cysts in the renal parenchyma. The cysts arise from renal tubules and are lined by abnormally functioning and hyperproliferative epithelial cells. Despite recent progress, no Fo...

Alternative Titles

Full title

miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696812

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3696812

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1301693110

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