Consequences of the combined loss of BOK and BAK or BOK and BAX
Consequences of the combined loss of BOK and BAK or BOK and BAX
About this item
Full title
Author / Creator
Ke, F , Bouillet, P , Kaufmann, T , Strasser, A , Kerr, J and Voss, A K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The multi-BCL-2 homology domain pro-apoptotic BCL-2 family members BAK and BAX have critical roles in apoptosis. They are essential for mitochondrial outer-membrane permeabilization, leading to the release of apoptogenic factors such as cytochrome-
c
, which promote activation of the caspase cascade and cellular demolition. The BOK protein ha...
Alternative Titles
Full title
Consequences of the combined loss of BOK and BAK or BOK and BAX
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3698543
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3698543
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2013.176
