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NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3700668

NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

About this item

Full title

NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

Publisher

United States: Nature Publishing Group

Journal title

Immunology and cell biology, 2013-07, Vol.91 (6), p.435-440

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

Tumor heterogeneity presents a substantial barrier to increasing clinical responses mediated by targeted therapies. Broadening the immune response elicited by treatments that target a single antigen is necessary for the elimination of tumor variants that fail to express the targeted antigen. In this study, it is shown that adoptive transfer of T ce...

Alternative Titles

Full title

NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3700668

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3700668

Other Identifiers

ISSN

0818-9641

E-ISSN

1440-1711

DOI

10.1038/icb.2013.17

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