Mechanisms of T-cell protection from death by IRX-2: a new immunotherapeutic
Mechanisms of T-cell protection from death by IRX-2: a new immunotherapeutic
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Scope and Contents
Contents
Objectives IRX-2 is a novel immunotherapeutic containing physiologic quantities of several cytokines which protects human T lymphocytes from tumor-induced or drug-induced apoptosis. Here, we investigate the mechanisms responsible for IRX-2-mediated protection of T lymphocytes exposed to tumor-derived microvesicles (TMV). Methods Jurkat cells or pri...
Alternative Titles
Full title
Mechanisms of T-cell protection from death by IRX-2: a new immunotherapeutic
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3708464
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3708464
Other Identifiers
ISSN
0340-7004
E-ISSN
1432-0851
DOI
10.1007/s00262-010-0951-9
