Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer mod...
Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model
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Publisher
New York: Elsevier Inc
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Language
English
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Publisher
New York: Elsevier Inc
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Scope and Contents
Contents
Accumulating evidence suggests that regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSC) are elevated in cancer patients and tumor-bearing hosts, and that depletion of Tregs and MDSC may enhance the anti-tumor immunity of the host. Sorafenib, a novel multi-kinase inhibitor, is approved for the treatment of several human cancers, i...
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Full title
Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3711234
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3711234
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ISSN
0023-6837,1530-0307
E-ISSN
1530-0307
DOI
10.1038/labinvest.2010.205
