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Refining comparative proteomics by spectral counting to account for shared peptides and multiple sea...

Refining comparative proteomics by spectral counting to account for shared peptides and multiple sea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3717168

Refining comparative proteomics by spectral counting to account for shared peptides and multiple search engines

About this item

Full title

Refining comparative proteomics by spectral counting to account for shared peptides and multiple search engines

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Analytical and bioanalytical chemistry, 2012-09, Vol.404 (4), p.1115-1125

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Spectral counting has become a widely used approach for measuring and comparing protein abundance in label-free shotgun proteomics. However, when analyzing complex samples, the ambiguity of matching between peptides and proteins greatly affects the assessment of peptide and protein inventories, differentiation, and quantification. Meanwhile, the co...

Alternative Titles

Full title

Refining comparative proteomics by spectral counting to account for shared peptides and multiple search engines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3717168

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3717168

Other Identifiers

ISSN

1618-2642

E-ISSN

1618-2650

DOI

10.1007/s00216-012-6011-x

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