Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mecha...
Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms
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Alexandria, VA: American Diabetes Association
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Language
English
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Alexandria, VA: American Diabetes Association
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Contents
Rapamycin is used frequently in both transplantation and oncology. Although historically thought to have little diabetogenic effect, there is growing evidence of β-cell toxicity. This Review draws evidence for rapamycin toxicity from clinical studies of islet and renal transplantation, and of rapamycin as an anticancer agent, as well as from experi...
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Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3717855
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3717855
Other Identifiers
ISSN
0012-1797,1939-327X
E-ISSN
1939-327X
DOI
10.2337/db13-0106
