Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11
Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background:
Mutations in
GNAQ
and
GNA11
, encoding the oncogenic G-protein alpha subunit q and 11, respectively, occur frequently in the majority of uveal melanomas.
Methods:
Exons 4 and 5 from
GNAQ
and
GNA11
were amplified and sequenced from 92 ciliary body and choroidal melanomas. The mutation status was correlate...
Alternative Titles
Full title
Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3721402
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3721402
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2013.299
