α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α
α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α
About this item
Full title
Author / Creator
Publisher
United States: American Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Thoracic Society
Subjects
More information
Scope and Contents
Contents
α₁-Antitrypsin (A1AT) is an acute-phase reactant, but also a major protective factor against the development of chronic obstructive pulmonary disease, a complex disease with sustained chronic inflammation. The lung-protective effects of A1AT have been attributed to the inhibition of proteases involved in lung matrix fragmentation, macrophage activa...
Alternative Titles
Full title
α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3727880
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3727880
Other Identifiers
ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2012-0515OC
