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The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3729939

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

About this item

Full title

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2012-12, Vol.13 (12), p.789-803

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
The chromosomal passenger complex (CPC) is a 'master controller' of cell division that is formed by a kinase module (Aurora B kinase) and a localization module (the scaffolding protein inner centromere protein (INCENP), survivin and borealin).
Multiple post-translational modifications of CPC components contribute to the appropriate...

Alternative Titles

Full title

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3729939

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3729939

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/nrm3474

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