A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis
A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis
About this item
Full title
Author / Creator
Sun, Xiao-Jian , Wang, Zhanxin , Wang, Lan , Jiang, Yanwen , Kost, Nils , Soong, T. David , Chen, Wei-Yi , Tang, Zhanyun , Nakadai, Tomoyoshi , Elemento, Olivier , Fischle, Wolfgang , Melnick, Ari , Patel, Dinshaw J. , Nimer, Stephen D. , Roeder, Robert G. and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
A multiprotein complex containing AML1–ETO, the most common fusion protein found in acute myeloid leukaemia, is revealed and analysed in leukaemic cells, and a novel, functionally important protein-binding interface is identified.
Fusion protein implicated in leukaemia
The fusion protein AML1–ETO is the most common chromosomal translocation f...
Alternative Titles
Full title
A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis
Authors, Artists and Contributors
Author / Creator
Wang, Zhanxin
Wang, Lan
Jiang, Yanwen
Kost, Nils
Soong, T. David
Chen, Wei-Yi
Tang, Zhanyun
Nakadai, Tomoyoshi
Elemento, Olivier
Fischle, Wolfgang
Melnick, Ari
Patel, Dinshaw J.
Nimer, Stephen D.
Roeder, Robert G.
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3732535
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3732535
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12287
