Vitamin C Controls the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
Vitamin C Controls the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
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Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Vitamin C (L-ascorbate) is present in the respiratory lining fluid of human lungs, and local deficits occur during oxidative stress. Here we report a unique function of vitamin C on the cystic fibrosis (CF) transmembrane conductance regulator (CFTR), cAMP-dependent Cl channel that regulates epithelial surface fluid secretion. Vitamin C (100 μM) ind...
Alternative Titles
Full title
Vitamin C Controls the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_373524
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_373524
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0308393100
