XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
About this item
Full title
Author / Creator
Huang, Xing , Wu, Zhengsheng , Mei, Yide and Wu, Mian
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
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More information
Scope and Contents
Contents
The primary role of autophagy is adaption to starvation. However, increasing evidence suggests that autophagy inhibition also plays an important role in tumorigenesis. Upregulation of X‐linked inhibitor of apoptosis (XIAP) has been associated to a variety of human cancers, yet the underlying mechanisms remain obscure. Here, we report that XIAP supp...
Alternative Titles
Full title
XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3746193
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3746193
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2013.133
