H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-depe...
H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway
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New York: Elsevier Inc
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Language
English
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New York: Elsevier Inc
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Histamine regulates many functions by binding to four histamine G-coupled receptor proteins (H1R, H2R, H3R and H4R). As H3R exerts their effects by coupling to Gαi/o proteins reducing adenosine 3′, 5′-monophosphate (cAMP) levels (a key player in the modulation of cholangiocyte hyperplasia/damage), we evaluated the role of H3R in the regulation of b...
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Full title
H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3751000
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3751000
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.3700533
