Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Deletions on chromososme 5q are associated with myelodysplastic lesions. The genes responsible have largely remained elusive. But use of an RNA interference-based approach that can identify haploinsufficient tumour suppressor genes identifies RPS14, which regulates ribosomal RNA processing as a candidate tumour suppressor gene responsible for this...
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Full title
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3771855
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3771855
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature06494
