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Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773365

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

About this item

Full title

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

Publisher

Boston: Springer US

Journal title

Journal of the American Society for Mass Spectrometry, 2013-10, Vol.24 (10), p.1584-1592

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Application of typical HDX methods to examine intrinsically disordered proteins (IDP), proteins that are natively unstructured and highly dynamic at physiological pH, is limited because of the rapid exchange of unprotected amide hydrogens with solvent. The exchange rates of these fast exchanging amides are usually faster than the shortest time scal...

Alternative Titles

Full title

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773365

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3773365

Other Identifiers

ISSN

1044-0305

E-ISSN

1879-1123

DOI

10.1007/s13361-013-0669-y

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