Endothelial Indoleamine 2,3-Dioxygenase Protects against Development of Pulmonary Hypertension
Endothelial Indoleamine 2,3-Dioxygenase Protects against Development of Pulmonary Hypertension
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Publisher
New York, NY: American Thoracic Society
Journal title
Language
English
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Publisher
New York, NY: American Thoracic Society
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Scope and Contents
Contents
A proliferative and apoptosis-resistant phenotype in pulmonary arterial smooth muscle cells (PASMCs) is key to pathologic vascular remodeling in pulmonary hypertension (PH). Expression of indoleamine-2,3-dioxygenase (IDO) by vascular endothelium is a newly identified vasomotor-regulatory mechanism also involved in molecular signaling cascades gover...
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Full title
Endothelial Indoleamine 2,3-Dioxygenase Protects against Development of Pulmonary Hypertension
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3778740
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3778740
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201304-0700OC