Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo
Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Background. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogues that silence expression of specific genes. We studied whether PPMOs targeted to essential genes in Acinetobacter Iwoffii and Acinetobacter baumannii are active in vitro and in vivo. Methods. PPMOs were evaluated in vitro using minimum inhi...
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Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3805245
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3805245
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jit460
