Inactivation of tumor‐specific CD8+ CTLs by tumor‐infiltrating tolerogenic dendritic cells
Inactivation of tumor‐specific CD8+ CTLs by tumor‐infiltrating tolerogenic dendritic cells
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Publisher
United States: Nature Publishing Group
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Language
English
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Publisher
United States: Nature Publishing Group
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Contents
Cancer immunosurveillance failure is largely attributed to the insufficient activation of tumor‐specific class I major histocompatibility complex (MHC) molecule (MHC‐I)‐restricted CD8+ cytotoxic T lymphocytes (CTLs). DEC‐205+ dendritic cells (DCs), having the ability to cross‐present, can present captured tumor antigens on MHC‐I alongside costimula...
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Full title
Inactivation of tumor‐specific CD8+ CTLs by tumor‐infiltrating tolerogenic dendritic cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3806489
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3806489
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ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1038/icb.2013.38
