Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury
Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury
About this item
Full title
Author / Creator
Hoff, Uwe , Lukitsch, Ivo , Chaykovska, Lyubov , Ladwig, Mechthild , Arnold, Cosima , Manthati, Vijay L. , Fuller, T. Florian , Schneider, Wolfgang , Gollasch, Maik , Muller, Dominik N. , Flemming, Bert , Seeliger, Erdmann , Luft, Friedrich C. , Falck, John R. , Dragun, Duska and Schunck, Wolf-Hagen
Publisher
Basingstoke: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
Basingstoke: Elsevier Inc
Subjects
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Scope and Contents
Contents
20-Hydroxyeicosatetraenoic acid (20-HETE) production is increased in ischemic kidney tissue and may contribute to ischemia/reperfusion (I/R) injury by mediating vasoconstriction and inflammation. To test this hypothesis, uninephrectomized male Lewis rats were exposed to warm ischemia following pretreatment with either an inhibitor of 20-HETE synthe...
Alternative Titles
Full title
Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3813968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3813968
Other Identifiers
ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2010.377
