Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by...
Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
p38α MAP kinase is activated by autophosphorylation, which is promoted by the protein TAB1 during myocardial ischemia and other stresses. Now cellular, biochemical and biophysical approaches reveal that TAB1 binds p38α's C-terminal kinase lobe and induces rearrangements within the activation segment that allow autophosphorylation
in cis
.
...
Alternative Titles
Full title
Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3822283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3822283
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2668
