The new low‐toxic histone deacetylase inhibitor S‐(2) induces apoptosis in various acute myeloid leu...
The new low‐toxic histone deacetylase inhibitor S‐(2) induces apoptosis in various acute myeloid leukaemia cells
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Author / Creator
Cellai, C. , Balliu, M. , Laurenzana, A. , Guandalini, L. , Matucci, R. , Miniati, D. , Torre, E. , Nebbioso, A. , Carafa, V. , Altucci, L. , Romanelli, M. N. and Paoletti, F.
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
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Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
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Scope and Contents
Contents
Histone deacetylase inhibitors (HDACi) induce tumour cell cycle arrest and/or apoptosis, and some of them are currently used in cancer therapy. Recently, we described a series of powerful HDACi characterized by a 1,4‐benzodiazepine (BDZ) ring hybridized with a linear alkyl chain bearing a hydroxamate function as Zn++‐chelating group. Here, we explo...
Alternative Titles
Full title
The new low‐toxic histone deacetylase inhibitor S‐(2) induces apoptosis in various acute myeloid leukaemia cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3822689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3822689
Other Identifiers
ISSN
1582-1838,1582-4934
E-ISSN
1582-4934
DOI
10.1111/j.1582-4934.2011.01464.x
