Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
About this item
Full title
Author / Creator
Kong, Leopold , Lee, Jeong Hyun , Doores, Katie J , Murin, Charles D , Julien, Jean-Philippe , McBride, Ryan , Liu, Yan , Marozsan, Andre , Cupo, Albert , Klasse, Per-Johan , Hoffenberg, Simon , Caulfield, Michael , King, C Richter , Hua, Yuanzi , Le, Khoa M , Khayat, Reza , Deller, Marc C , Clayton, Thomas , Tien, Henry , Feizi, Ten , Sanders, Rogier W , Paulson, James C , Moore, John P , Stanfield, Robyn L , Burton, Dennis R , Ward, Andrew B and Wilson, Ian A
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Some broadly neutralizing antibodies to HIV-1 recognize glycan-dependent epitopes on gp120. Now X-ray crystallography and EM approaches, along with functional analyses, reveal how one particular antibody (PGT135) recognizes three glycan groups and can accommodate their conformational and chemical diversity.
A substantial proportion of the broadl...
Alternative Titles
Full title
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Authors, Artists and Contributors
Author / Creator
Lee, Jeong Hyun
Doores, Katie J
Murin, Charles D
Julien, Jean-Philippe
McBride, Ryan
Liu, Yan
Marozsan, Andre
Cupo, Albert
Klasse, Per-Johan
Hoffenberg, Simon
Caulfield, Michael
King, C Richter
Hua, Yuanzi
Le, Khoa M
Khayat, Reza
Deller, Marc C
Clayton, Thomas
Tien, Henry
Feizi, Ten
Sanders, Rogier W
Paulson, James C
Moore, John P
Stanfield, Robyn L
Burton, Dennis R
Ward, Andrew B
Wilson, Ian A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3823233
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3823233
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2594
