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Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Sm...

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Sm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3828896

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad‐independent TGF‐β pathway – implication of C‐Krox and Sp1

About this item

Full title

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad‐independent TGF‐β pathway – implication of C‐Krox and Sp1

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

Journal of cellular and molecular medicine, 2008-12, Vol.12 (6b), p.2836-2847

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Despite several investigations, the transcriptional mechanisms which regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either physiological or pathological situations, such as scleroderma, are not completely known. In this study, we determined the effects of both native ichtyan chondroïtin sulphate (CS) and its derived hy...

Alternative Titles

Full title

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad‐independent TGF‐β pathway – implication of C‐Krox and Sp1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3828896

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3828896

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/j.1582-4934.2008.00287.x

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