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Simvastatin reduces melanoma progression in a murine model

Simvastatin reduces melanoma progression in a murine model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3833984

Simvastatin reduces melanoma progression in a murine model

About this item

Full title

Simvastatin reduces melanoma progression in a murine model

Publisher

Athens: D.A. Spandidos

Journal title

International journal of oncology, 2013-12, Vol.43 (6), p.1763-1770

Language

English

Formats

Publication information

Publisher

Athens: D.A. Spandidos

More information

Scope and Contents

Contents

Statins are a class of drugs that inhibit the rate-limiting step in the cholesterol biosynthetic pathway and show an anticancer effect, probably through the inhibition of cell proliferation. To date, the exact mechanism of cancer cell growth arrest induced by statins is not known. We report that simvastatin is able to induce apoptosis in melanoma c...

Alternative Titles

Full title

Simvastatin reduces melanoma progression in a murine model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3833984

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3833984

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2013.2126

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