Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glyco...
Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
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Full title
Author / Creator
von Wilamowitz-Moellendorff, Alexander , Hunter, Roger W. , García-Rocha, Mar , Kang, Li , López-Soldado, Iliana , Lantier, Louise , Patel, Kashyap , Peggie, Mark W. , Martínez-Pons, Carlos , Voss, Martin , Calbó, Joaquim , Cohen, Patricia T.W. , Wasserman, David H. , Guinovart, Joan J. and Sakamoto, Kei
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
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Publication information
Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
The liver responds to an increase in blood glucose levels in the postprandial state by uptake of glucose and conversion to glycogen. Liver glycogen synthase (GYS2), a key enzyme in glycogen synthesis, is controlled by a complex interplay between the allosteric activator glucose-6-phosphate (G6P) and reversible phosphorylation through glycogen synth...
Alternative Titles
Full title
Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3837029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3837029
Other Identifiers
ISSN
0012-1797,1939-327X
E-ISSN
1939-327X
DOI
10.2337/db13-0880
