PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White...
PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders
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Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
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Publication information
Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and insulin sensitivity, especially when fed a high-fat...
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Full title
PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3837041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3837041
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db13-0518