Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel
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Publisher
Australia: Blackwell Publishing Ltd
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Language
English
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Australia: Blackwell Publishing Ltd
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Summary
The G‐protein‐activated inwardly rectifying potassium channel Kir3.4 is expressed in the zona glomerulosa cell membrane and transports potassium out of the cell.
Angiotensin II stimulation of aldosterone secretion is mediated, in part, by suppression of the transcription of KCNJ5, the gene coding for Kir3.4, and blocking channel act...
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Full title
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3838480
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3838480
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ISSN
0305-1870,1440-1681
E-ISSN
1440-1681
DOI
10.1111/1440-1681.12151
