Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
It is unclear whether bidirectional non-coding RNAs transcribed from enhancer elements (eRNAs) have any functional role; here, the repressive functions of Rev-Erb nuclear receptors in macrophages are shown to be linked to their ability to inhibit the transcription of eRNAs.
Regulatory role for eRNAs
Bidirectional non-coding RNAs are transcrib...
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Full title
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839578
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839578
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12209