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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839578

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

About this item

Full title

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2013-06, Vol.498 (7455), p.511-515

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It is unclear whether bidirectional non-coding RNAs transcribed from enhancer elements (eRNAs) have any functional role; here, the repressive functions of Rev-Erb nuclear receptors in macrophages are shown to be linked to their ability to inhibit the transcription of eRNAs.
Regulatory role for eRNAs
Bidirectional non-coding RNAs are transcrib...

Alternative Titles

Full title

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839578

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3839578

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature12209

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