Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T...
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Jameson and colleagues show that the establishment of resident memory CD8
+
T cells in nonlymphoid tissues requires transcriptional downregulation of the trafficking molecule S1P
1
, mediated by induced loss of the transcription factor KLF2.
Cell-mediated immunity critically depends on the localization of lymphocytes at sites of infe...
Alternative Titles
Full title
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3844557
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3844557
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2745
