Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemicha...
Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Chronic musculoskeletal pain involves connective tissue remodeling triggered by inflammatory mediators, such as bradykinin. Fibroblast cells signaling involve changes in intracellular Ca2+ ([Ca2+]i). ATP has been related to connective tissue mechanotransduction, remodeling and chronic inflammatory pain, via P2 purinoceptors activation. Here, we inv...
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Full title
Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3848849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3848849
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/1478-811X-11-70
