The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging
The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Anti-CD20 Ab therapy has proven successful for treating B cell malignancies and a number of autoimmune diseases. However, how anti-CD20 Abs operate in vivo to mediate B cell depletion is not fully understood. In particular, the anatomical location, the type of effector cells, and the mechanism underlying anti-CD20 therapy remain uncertain. Here, we...
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Full title
The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859399
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI70972