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The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859399

The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

About this item

Full title

The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2013-12, Vol.123 (12), p.5098-5103

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Anti-CD20 Ab therapy has proven successful for treating B cell malignancies and a number of autoimmune diseases. However, how anti-CD20 Abs operate in vivo to mediate B cell depletion is not fully understood. In particular, the anatomical location, the type of effector cells, and the mechanism underlying anti-CD20 therapy remain uncertain. Here, we...

Alternative Titles

Full title

The mechanism of anti-CD20–mediated B cell depletion revealed by intravital imaging

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859399

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI70972

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