Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
About this item
Full title
Author / Creator
Lam, Hilaire C , Cloonan, Suzanne M , Bhashyam, Abhiram R , Haspel, Jeffery A , Singh, Anju , Sathirapongsasuti, J Fah , Cervo, Morgan , Yao, Hongwei , Chung, Anna L , Mizumura, Kenji , An, Chang Hyeok , Shan, Bin , Franks, Jonathan M , Haley, Kathleen J , Owen, Caroline A , Tesfaigzi, Yohannes , Washko, George R , Quackenbush, John , Silverman, Edwin K , Rahman, Irfan , Kim, Hong Pyo , Mahmood, Ashfaq , Biswal, Shyam S , Ryter, Stefan W and Choi, Augustine M K
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Chronic obstructive pulmonary disease (COPD) involves aberrant airway inflammatory responses to cigarette smoke (CS) that are associated with epithelial cell dysfunction, cilia shortening, and mucociliary clearance disruption. Exposure to CS reduced cilia length and induced autophagy in vivo and in differentiated mouse tracheal epithelial cells (MT...
Alternative Titles
Full title
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
Authors, Artists and Contributors
Author / Creator
Cloonan, Suzanne M
Bhashyam, Abhiram R
Haspel, Jeffery A
Singh, Anju
Sathirapongsasuti, J Fah
Cervo, Morgan
Yao, Hongwei
Chung, Anna L
Mizumura, Kenji
An, Chang Hyeok
Shan, Bin
Franks, Jonathan M
Haley, Kathleen J
Owen, Caroline A
Tesfaigzi, Yohannes
Washko, George R
Quackenbush, John
Silverman, Edwin K
Rahman, Irfan
Kim, Hong Pyo
Mahmood, Ashfaq
Biswal, Shyam S
Ryter, Stefan W
Choi, Augustine M K
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859407
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3859407
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI69636
