Id4 dependent acetylation restores mutant-p53 transcriptional activity
Id4 dependent acetylation restores mutant-p53 transcriptional activity
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The mechanisms that can restore biological activity of mutant p53 are an area of high interest given that mutant p53 expression is observed in one third of prostate cancer. Here we demonstrate that Id4, an HLH transcriptional regulator and a tumor suppressor, can restore the mutant p53 transcriptional activity in prostate cancer cells.
Id4 was o...
Alternative Titles
Full title
Id4 dependent acetylation restores mutant-p53 transcriptional activity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3866570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3866570
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-12-161
