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Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3868047

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

About this item

Full title

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

Publisher

United States: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.188-202

Language

English

Formats

Publication information

Publisher

United States: American Diabetes Association

More information

Scope and Contents

Contents

Type 1 diabetes is characterized by infiltration of pancreatic islets with immune cells, leading to insulin deficiency. Although infiltrating immune cells are traditionally considered to negatively impact β-cells by promoting their death, their contribution to proliferation is not fully understood. Here we report that islets exhibiting insulitis al...

Alternative Titles

Full title

Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3868047

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3868047

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/db13-0204

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