Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancrea...
Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid
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Author / Creator
Ræder, Helge , McAllister, Fiona E , Tjora, Erling , Bhatt, Shweta , Haldorsen, Ingfrid , Hu, Jiang , Willems, Stefan M , Vesterhus, Mette , El Ouaamari, Abdelfattah , Liu, Manway , Ræder, Maria B , Immervoll, Heike , Hoem, Dag , Dimcevski, Georg , Njølstad, Pål R , Molven, Anders , Gygi, Steven P and Kulkarni, Rohit N
Publisher
United States: American Diabetes Association
Journal title
Language
English
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Publication information
Publisher
United States: American Diabetes Association
Subjects
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Scope and Contents
Contents
Carboxyl-ester lipase (CEL) maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes and pancreatic exocrine dysfunction due to mutations in the CEL gene encoding CEL. The pathogenic mechanism for diabetes development is unknown. Since CEL is expressed mainly in pancreatic acinar cells, we asked whether we could find structural p...
Alternative Titles
Full title
Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3868055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3868055
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db13-1012