Isolation and Sequence Determination of a cDNA Clone Related to Human Cytochrome P-450 Nifedipine Ox...
Isolation and Sequence Determination of a cDNA Clone Related to Human Cytochrome P-450 Nifedipine Oxidase
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
Human liver cytochrome P-450NFis the form of cytochrome P-450 responsible for the oxidation of the calcium-channel blocker nifedipine, which has been reported to show polymorphism in clinical studies. By screening a bacteriophage λ gt11 expression cDNA library, we isolated two clones: NF95 with an insert length of 0.8 kilobases which gave a stable...
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Full title
Isolation and Sequence Determination of a cDNA Clone Related to Human Cytochrome P-450 Nifedipine Oxidase
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_386867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_386867
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.83.21.8064
