Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with h...
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
About this item
Full title
Author / Creator
Bezzina, Connie R , Barc, Julien , Mizusawa, Yuka , Remme, Carol Ann , Gourraud, Jean-Baptiste , Simonet, Floriane , Verkerk, Arie O , Schwartz, Peter J , Crotti, Lia , Dagradi, Federica , Guicheney, Pascale , Fressart, Véronique , Leenhardt, Antoine , Antzelevitch, Charles , Bartkowiak, Susan , Borggrefe, Martin , Schimpf, Rainer , Schulze-Bahr, Eric , Zumhagen, Sven , Behr, Elijah R , Bastiaenen, Rachel , Tfelt-Hansen, Jacob , Olesen, Morten Salling , Kääb, Stefan , Beckmann, Britt M , Weeke, Peter , Watanabe, Hiroshi , Endo, Naoto , Minamino, Tohru , Horie, Minoru , Ohno, Seiko , Hasegawa, Kanae , Makita, Naomasa , Nogami, Akihiko , Shimizu, Wataru , Aiba, Takeshi , Froguel, Philippe , Balkau, Beverley , Lantieri, Olivier , Torchio, Margherita , Wiese, Cornelia , Weber, David , Wolswinkel, Rianne , Coronel, Ruben , Boukens, Bas J , Bézieau, Stéphane , Charpentier, Eric , Chatel, Stéphanie , Despres, Aurore , Gros, Françoise , Kyndt, Florence , Lecointe, Simon , Lindenbaum, Pierre , Portero, Vincent , Violleau, Jade , Gessler, Manfred , Tan, Hanno L , Roden, Dan M , Christoffels, Vincent M , Le Marec, Hervé , Wilde, Arthur A , Probst, Vincent , Schott, Jean-Jacques , Dina, Christian and Redon, Richard
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Connie Bezzina, Richard Redon and colleagues show that common variants at
SCN5A
-
SCN10A
and
HEY2
are associated with Brugada syndrome, a rare disorder with high risk of sudden cardiac death. The newly discovered loci have a large cumulative effect on disease risk and illustrate how common variants can have a strong impact on pred...
Alternative Titles
Full title
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
Authors, Artists and Contributors
Author / Creator
Barc, Julien
Mizusawa, Yuka
Remme, Carol Ann
Gourraud, Jean-Baptiste
Simonet, Floriane
Verkerk, Arie O
Schwartz, Peter J
Crotti, Lia
Dagradi, Federica
Guicheney, Pascale
Fressart, Véronique
Leenhardt, Antoine
Antzelevitch, Charles
Bartkowiak, Susan
Borggrefe, Martin
Schimpf, Rainer
Schulze-Bahr, Eric
Zumhagen, Sven
Behr, Elijah R
Bastiaenen, Rachel
Tfelt-Hansen, Jacob
Olesen, Morten Salling
Kääb, Stefan
Beckmann, Britt M
Weeke, Peter
Watanabe, Hiroshi
Endo, Naoto
Minamino, Tohru
Horie, Minoru
Ohno, Seiko
Hasegawa, Kanae
Makita, Naomasa
Nogami, Akihiko
Shimizu, Wataru
Aiba, Takeshi
Froguel, Philippe
Balkau, Beverley
Lantieri, Olivier
Torchio, Margherita
Wiese, Cornelia
Weber, David
Wolswinkel, Rianne
Coronel, Ruben
Boukens, Bas J
Bézieau, Stéphane
Charpentier, Eric
Chatel, Stéphanie
Despres, Aurore
Gros, Françoise
Kyndt, Florence
Lecointe, Simon
Lindenbaum, Pierre
Portero, Vincent
Violleau, Jade
Gessler, Manfred
Tan, Hanno L
Roden, Dan M
Christoffels, Vincent M
Le Marec, Hervé
Wilde, Arthur A
Probst, Vincent
Schott, Jean-Jacques
Dina, Christian
Redon, Richard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3869788
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3869788
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2712
