Effects of Genetic Variation at the CYP2C19 / CYP2C9 Locus on Pharmacokinetics of Chlorcycloguanil i...
Effects of Genetic Variation at the CYP2C19 / CYP2C9 Locus on Pharmacokinetics of Chlorcycloguanil in Adult Gambians
About this item
Full title
Author / Creator
Publisher
England: Future Medicine Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Future Medicine Ltd
Subjects
More information
Scope and Contents
Contents
Antimalarial biguanides are metabolized by CYP2C19, thus genetic variation at the CYP2C locus might affect pharmacokinetics and so treatment outcome for malaria.
Polymorphisms in CYP2C19 and CYP2C9 in 43 adult Gambians treated with chlorproguanil/dapsone for uncomplicated malaria were assessed. Chlorcycloguanil pharmacokinetics were measured and...
Alternative Titles
Full title
Effects of Genetic Variation at the CYP2C19 / CYP2C9 Locus on Pharmacokinetics of Chlorcycloguanil in Adult Gambians
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3870622
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3870622
Other Identifiers
ISSN
1462-2416
E-ISSN
1744-8042
DOI
10.2217/pgs.09.72
