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Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3875954

Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

About this item

Full title

Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2013-11, Vol.5 (4), p.1566-1576

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. RASSFs are a family of tumor suppressors that are frequently inactivated by promoter hypermethylation in various cancers. We studied CpG island promoter hypermethylation in MCC of RASSF2, RASSF5A, RASSF5C and RASSF10 by combined bisulfite restriction analysis (COBRA) in...

Alternative Titles

Full title

Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3875954

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3875954

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers5041566

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