NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1
NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The biological function of NF-κB1 (p50) in the regulation of protein expression is far from well understood owing to the lack of a transcriptional domain. Here, we report a novel function of p50 in its regulation of p53 protein translation under stress conditions. We found that the deletion of p50 (p50−/−) impaired arsenite-induced p53 protein expr...
Alternative Titles
Full title
NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883870
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3883870
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2013.8
